TY - JOUR T1 - Hospital mortality in cirrhotic patients at a tertiary care center JO - Revista de Gastroenterología de México T2 - AU - Zubieta-Rodríguez,R. AU - Gómez-Correa,J. AU - Rodríguez-Amaya,R. AU - Ariza-Mejia,K.A. AU - Toloza-Cuta,N.A. SN - 2255534X M3 - 10.1016/j.rgmxen.2016.10.005 DO - 10.1016/j.rgmxen.2016.10.005 UR - http://www.revistagastroenterologiamexico.org/en-hospital-mortality-in-cirrhotic-patients-articulo-S2255534X17300464 AB - IntroductionCirrhosis of the liver is known for its high risk of mortality associated with episodes of acute decompensation. There is an even greater risk in patients that present with acute-on-chronic liver failure. The identification of patients at higher risk for adverse outcomes can aid in making the clinical decisions that will improve the prognosis for these patients. AimsTo determine in-hospital mortality and evaluate the epidemiologic and clinical characteristics of patients with cirrhosis of the liver seen at a tertiary referral hospital. MethodologyA descriptive, observational, cohort study was conducted on adult patients with cirrhosis of the liver, admitted to a tertiary care center in Bucaramanga, Colombia, within the time frame of March 1, 2015 and February 29, 2016. ResultsEighty-one patients with a mean age of 62 years were included in the study. The main etiology of the cirrhosis was alcoholic (59.3%). In-hospital mortality was 23.5% and the most frequent cause of death was septic shock (68.4%), followed by hypovolemic shock (10.5%). A MELD score≥18, a leukocyte count>12,000/ul, and albumin levels below<2.5g/dl were independent factors related to hospital mortality. ConclusionsIn-hospital mortality in cirrhotic patients is high. Sepsis and bleeding are the 2 events leading to acute-on-chronic liver failure and death. A high MELD score, elevated leukocyte count, and low level of albumin are related to poor outcome during hospitalization. Adjusted prevention-centered public health measures and early and opportune diagnosis of this disease are needed to prevent the development of complications and to improve outcome in cirrhotic patients. ER -