TY - JOUR T1 - Iron-deficiency anemia as a subclinical celiac disease presentation in an Argentinian population JO - Revista de GastroenterologĂ­a de MĂ©xico T2 - AU - Lasa,J.S. AU - Olivera,P. AU - Soifer,L. AU - Moore,R. SN - 2255534X M3 - 10.1016/j.rgmxen.2016.12.004 DO - 10.1016/j.rgmxen.2016.12.004 UR - http://www.revistagastroenterologiamexico.org/en-iron-deficiency-anemia-as-subclinical-celiac-articulo-S2255534X1730052X AB - BackgroundThere is a wide heterogeneity in the reports of celiac disease prevalence in iron-deficiency anemia patients. AimTo determine the prevalence of celiac disease in patients with iron-deficiency anemia. Materials and methodsAdult patients with a diagnosis of iron-deficiency anemia were enrolled for upper endoscopy with duodenal biopsies. Volunteers that underwent upper endoscopy were enrolled as controls. ResultsA total of 135 patients with iron-deficiency anemia and 133 controls were enrolled. Celiac disease prevalence was higher in the iron-deficiency anemia group [11.11 vs. 1.51%, OR: 8.18 (1.83-36.55), P=.001). Of the celiac disease patients in the iron-deficiency anemia group, 73.3% had at least one endoscopic sign suggesting villous atrophy, whereas 100% of the celiac disease patients in the control group presented with at least one endoscopic sign. ConclusionsPatients with iron-deficiency anemia have an increased risk for celiac disease. Up to 25% of these patients may not present any endoscopic sign suggesting villous atrophy. ER -