TY - JOUR T1 - Prevalence of eosinophilic esophagitis: A multicenter study on a pediatric population evaluated at thirty-six Latin American gastroenterology centers JO - Revista de Gastroenterología de México T2 - AU - Pierre,R. AU - Vieira,M. AU - Vázquez,R. AU - Ninomiya,I. AU - Messere,G. AU - Daza,W. AU - Dadan,S. AU - Higuera,M. AU - Sifontes,L. AU - Harris,P. AU - Gana,J.C. AU - Rodríguez,M. AU - Vasquez,M. AU - González,M. AU - Rivera,J. AU - Gonzales,J. AU - Angulo,D. AU - Cetraro,M.D. AU - Del Compare,M. AU - López,K. AU - Navarro,D. AU - Calva,R. AU - Wagener,M. AU - Zablah,R. AU - Carias,A. AU - Calderón,O. AU - Vera-Chamorro,J.F. AU - Toca,M.C. AU - Dewaele,M.R. AU - Iglesias,C. AU - Delgado,L. AU - León,K. AU - Hassan,I. AU - Ussher,F. AU - Follett,F. AU - Bernedo,V. AU - Grinblat,V. AU - Agüero,N. AU - Oviedo,C. AU - García,A.G. AU - Salazar,A. AU - Coello,P. AU - Furnes,R. AU - Menchaca,M. AU - Fernández,M. AU - Khoury,A. AU - Rojo,C. AU - Fernández,S. AU - Morao,C. SN - 2255534X M3 - 10.1016/j.rgmxen.2018.10.002 DO - 10.1016/j.rgmxen.2018.10.002 UR - http://www.revistagastroenterologiamexico.org/en-prevalence-eosinophilic-esophagitis-a-multicenter-articulo-S2255534X18301427 AB - Introduction and objectiveEosinophilic esophagitis is a chronic, immune-mediated disease described in case series and publications worldwide. Over the past twenty years, the authors of different studies have attempted to evaluate its incidence and prevalence. The objetive of the present study was to estimate the prevalence of eosinophilic esophagitis in a group of children seen at 36 pediatric gastroenterology centers in ten Latin American countries. Materials and methodsA multicenter, observational, and cross-sectional study was conducted that estimated the period prevalence of eosinophilic esophagitis in children seen at outpatient consultation and that underwent diagnostic upper gastrointestinal endoscopy for any indication at 36 centers in 10 Latin American countries, within a 3-month time frame. ResultsBetween April and June 2016, 108 cases of eosinophilic esophagitis were evaluated. Likewise, an average of 29,253 outpatient consultations and 4,152 diagnostic upper gastrointestinal endoscopies were carried out at the 36 participating centers. The period prevalence of eosinophilic esophagitis in the population studied (n=29,253) was 3.69 cases×1,000 (95% CI: 3.04 to 4.44), and among the children that underwent routine upper gastrointestinal endoscopy (n=4,152), it was 26x1,000 (95% CI: 22.6 to 29.4). ConclusionsThe general period prevalence of eosinophilic esophagitis in a group of children evaluated at 36 Latin American pediatric gastroenterology centers was 3.69×1,000, and in the children that underwent endoscopy, it was 26×1,000. There was important prevalence variability between the participating countries and centers. The present analysis is the first study conducted on the prevalence of pediatric eosinophilic esophagitis in Latin America. ER -