TY - JOUR T1 - Association of laboratory and radiologic parameters in the diagnosis of acute cholecystitis JO - Revista de Gastroenterología de México T2 - AU - Menéndez-Sánchez,P. AU - León-Salinas,C. AU - Amo-Salas,M. AU - Méndez-Cea,B. AU - García-Carranza,A. SN - 2255534X M3 - 10.1016/j.rgmxen.2019.02.007 DO - 10.1016/j.rgmxen.2019.02.007 UR - http://www.revistagastroenterologiamexico.org/en-association-laboratory-radiologic-parameters-in-articulo-S2255534X19300155 AB - Introduction and objectivesThere is currently more evidence suggesting that early surgery should be the treatment of choice for acute calculous cholecystitis, although initial conservative treatment is also reported to be safe. Treatment decision depends on the conditions of the patient, surgical experience, and hospital infrastructure, given that early surgery cannot always be carried out. The aim of the present study was to correlate C-reactive protein values with other variables to determine those situations in which surgery cannot be delayed. Materials and methodsA retrospective study was conducted on patients admitted to the hospital from the emergency service with the diagnosis of acute calculous cholecystitis. The patients were divided into 2groups: 1) patients that required urgent cholecystectomy and 2) patients that responded well to conservative medical treatment and later underwent deferred cholecystectomy. ResultsA total of 238 patients (♂ 54.6%, ♀ 45.4%) were analyzed. Urgent surgery was performed on 158 patients, whereas the remaining 80 patients were released from the hospital following conservative treatment. The odds ratio of gangrenous cholecystitis presenting in acute cholecystitis for C-reactive protein was calculated in the logistic regression analysis, obtaining an OR of 1.088 and a 95% CI of 1.031-1.121. ConclusionIn patients diagnosed with acute calculous cholecystitis, the combination of elevated values of C-reactive protein levels, gallbladder wall thickness, and number of leukocytes was correlated with less favorable clinical and gallbladder histologic states, resulting in a greater need for urgent surgical treatment. ER -