TY - JOUR T1 - Liver transplantation in Mexican older adults: A comparative single-center study JO - Revista de Gastroenterología de México T2 - AU - Hernández-Ruiz,V. AU - García-Lara,J.M.A. AU - Zamudio-Rodríguez,A. AU - García-Juárez,I. AU - Avila-Funes,J.A. SN - 2255534X M3 - 10.1016/j.rgmxen.2018.09.012 DO - 10.1016/j.rgmxen.2018.09.012 UR - http://www.revistagastroenterologiamexico.org/en-liver-transplantation-in-mexican-older-articulo-S2255534X19300982 AB - IntroductionLiver disease is currently one of the leading causes of death in older adults and the only option deemed curative is liver transplantation. However, it is uncertain whether the successful results obtained in older adults that receive a liver transplant in developed countries can be replicated in developing countries. AimTo determine if there are differences in the survival time between older (≥60 years) and younger adults that underwent liver transplantation at a university-affiliated tertiary care center in Mexico City. Materials and methodsA 2-year longitudinal study was conducted. It included 244 participants that were divided into 2 groups according to age at the time of transplantation: older adults (≥60 years) and younger adults (18–59 years). Survival time was defined as the number of days that elapsed between transplantation and death. Survival was expressed as Kaplan-Meier curves. ResultsMedian age in the older adults (n=52) was 63.0 (IQR=60–69) and 23 participants were females (44.2%). In the younger adults (n=196) median age was 47.0 (IQR=16–59) and 104 were females (52%). The leading indication for transplant was hepatitis C virus. After the follow-up, fifteen participants died (twelve younger adults and three older adults). No significant differences were observed between older and younger participants in postoperative complications, the number of re-admissions, or mean post-transplantation survival time. ConclusionsThere were no statistically significant differences in relation to survival times between older and younger adults that received a liver transplant. Older patients in developing countries should not be excluded from the selection process due only to age. ER -