TY - JOUR T1 - Better quality of life and reduced fecal incontinence in rectal cancer patients with the watch-and-wait follow-up strategy JO - Revista de Gastroenterología de México T2 - AU - Pascual-Russo,A. AU - Milito,D. AU - Facio,L. AU - Furia,M. AU - Forestier,V. AU - Iseas,S. AU - Méndez,G. AU - Coraglio,M. AU - Lumi,C.M. AU - Masciangioli,G. AU - Mauriño,E. AU - Vázquez,H. SN - 2255534X M3 - 10.1016/j.rgmxen.2020.07.009 DO - 10.1016/j.rgmxen.2020.07.009 UR - http://www.revistagastroenterologiamexico.org/en-better-quality-life-reduced-fecal-articulo-S2255534X21000736 AB - IntroductionThe watch-and-wait (WW) strategy is an alternative to anterior resection in patients with rectal cancer (RC) that have had a complete clinical response to neoadjuvant treatment. Few reports describe the quality of life and functional anorectal disorders (FADs) in that population. AimTo analyze and compare the FADs and quality of life in patients with locally advanced adenocarcinoma of the rectum treated with neoadjuvant therapy, divided into two different strategy groups: group 1 (G1), WW; and group 2 (G2), anterior resection. Materials and methodsThirty patients (G1: n = 20 and G2: n = 10) that had finished neoadjuvant therapy at least 12 months prior were included. Mean patient age was 59.5 years (range: 41-79) and 15 of the patients were men. The FADs were evaluated through: a) clinical history, b) 21-day bowel diary, c) Jorge and Wexner fecal incontinence scale, d) anorectal manometry (ARM), and fecal incontinence quality of life scale (FIQL). ResultsBowel diary: fecal incontinence (40%) and urge to defecate (45%) in G1 vs. fecal incontinence (60%) and urge to defecate (30%) in G2, with no significant differences (p = NS). Fecal incontinence scale: fecal incontinence in G1 was significantly less severe than that in G2 (median 6.5 points vs. 13 points [p = 0.0142]). ARM: no differences between the two groups. Quality of life: significantly different between the two groups (FIQL/G1: 3.7 vs. FIQL/G2: 2.8; p < 0.03). ConclusionsThe WW follow-up strategy in patients with locally advanced rectal cancer was associated with better quality of life and reduced fecal incontinence. ER -