Original article—liver, pancreas, and biliary tractAcute Pancreatitis During Pregnancy
Section snippets
Patients
This was a retrospective study over a 6-year period (September 2000–September 2006) at PMH and was approved by the University of Texas Southwestern Medical Center Institutional Review Board. Through computerized diagnostic codes entered on discharge, all consecutive pregnant patients who were admitted for acute pancreatitis or developed acute pancreatitis during hospitalization were identified. A computerized database was established in 2000 at PMH and patients were registered. The patient
Clinical Characteristics of Acute Pancreatitis in Pregnancy
The annual birth rates were as follows: 16,504 (in 2001), 15,677 (in 2002), 15,549 (in 2003), 16,223 (in 2004), 15,972 (in 2005), and 16,307 (in 2006), totaling 96,232 deliveries during the study period (Figure 1). Ninety-six patients were admitted for acute pancreatitis. The calculated rate of spontaneous acute pancreatitis in pregnancy was thus 1 per 998 births (0.1%). In addition, 7 patients without pre-procedure pancreatitis developed post-ERCP pancreatitis, resulting in a total of 103
Discussion
In this study, although favorable outcomes can be expected in the majority of patients with acute pancreatitis occurring during pregnancy, adverse fetal outcomes (fetal loss and preterm delivery) occurring during the first trimester were prominent. Acute pancreatitis complicated by DIC usually occurs in the third trimester and is particularly associated with poor fetal and maternal outcomes. Acute pancreatitis during pregnancy in the United States was once thought to be rare but appears now to
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Acute pancreatitis in pregnancy and its impact on the maternal and foetal outcomes: A systematic review
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Conflicts of interest The authors disclose no conflicts.