Original articleClinical endoscopyComparison of standard forward-viewing mode versus ultrawide-viewing mode of a novel colonoscopy platform: a prospective, multicenter study in the detection of simulated polyps in an in vitro colon model (with video)
Section snippets
Methods and materials
This was a multicenter, prospective study whereby gastroenterologists, experienced in performing colonoscopy, were asked to complete a standard colonoscopy screening procedure in a medical facility procedure room by using a silicone colon model and to identify “simulated” colon polyps attached to the colon model wall.
Results
In total, 37 endoscopists (32 male, 49.2 ± 8.7 years old, 16.7 ± 11.1 years in practice) participated at 6 centers located in the United States (n = 3) and Israel (n = 3). All 37 endoscopists (100%) successfully inserted and advanced the PeerScope System Model B colonoscope to the cecum. On colonoscope withdrawal by using the forward-viewing mode, the number of simulated polyps (mean ± standard deviation) detected per endoscopist was 11.1 ± 2.3 polyps, a 52.9% simulated polyp detection rate.
Discussion
Multiple studies, in varied patient populations, have shown significant adenoma miss rates during forward-viewing, optical colonoscopy.5, 6, 7, 8, 9, 10, 11 Rex et al6 performed back-to-back colonoscopies on 183 patients and reported a 24% adenoma miss rate. This included miss rates of 27% for adenomas 5 mm or smaller, 13% for adenomas 6 to 9 mm, and even a 6% miss rate for adenomas 10 mm or larger. Moreover, adenoma miss rates varied widely even among senior endoscopists, ranging from 17% to
Acknowledgments
We thank and acknowledge all of the participating endoscopists: Drs Abittan, Anikin, Ascunce, Bedmanrek, Bernstein, Bouck, Carr-Locke, Chowers, Cohen, Dekel, Dickstein, Fenster, Nascembeni Ferran, Halak, Halpern, Kadish, Karaban, Kasmin, Khamyasi, Lachter, Lewis, Merdler, Milham, Milkes, Novelrudsky, Rattner, Santo, Scapa, Shapil, Shapira, Sloyer, Suissa, Talansky, Ugran, Yanay, Yassin, and Zeitan.
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DISCLOSURE: Drs Gralnek, Halpern, Siersema, Carr-Locke, Segol, and Suissa are consultants for Peer Medical Ltd. Dr Segev is the Medical Director of Peer Medical Ltd. This study was sponsored by Peer Medical Ltd, Caesaria, Israel.