New methodsExperimental endoscopySimplified magnetic anchor-guided endoscopic submucosal dissection in dogs (with videos)
Section snippets
Test subjects
This study was approved by the Institute for Laboratory Animal Research at the Nagoya University Graduate School of Medicine in Japan (no. 25267), and was conducted in compliance with the laws for the humane treatment and management of animals. Two female beagle dogs (17 and 18 kg) were laid in the left lateral position on an examination table under intravenous anesthesia using propofol and pentazocine in intubated animals. Ten different representative areas were predetermined with coagulation
Results
Simplified MAG-ESDs using neodymium magnets were successfully performed in all cases without perforation (Fig. 2; Table 2; Videos 1 and 2, available online at www.giejournal.org). Adequate countertraction with good visualization was obtained using the external magnet.
In 8 cases, direct visualization was facilitated by an external magnet (magnetic attraction force, 382.9 N; magnetic flux density, 398 mT) (Fig. 1A, Table 1). However, in 2 cases, adequate countertraction could not be applied in
Discussion
Simplified MAG-ESDs using neodymium magnets were successfully performed in various representative areas of the beagle dog stomach. The magnetic anchor could be controlled, and adequate countertraction was obtained using the external magnet. In the case of a location at the posterior wall of the gastric angle, an additional magnetic anchor was necessary to facilitate good visualization for submucosal dissection. This may be caused by the distance between the external and internal magnets.
Several
References (22)
- et al.
Thin endoscope-assisted endoscopic submucosal dissection for large colorectal tumors (with videos)
Gastrointest Endosc
(2007) - et al.
A new technique for gastric endoscopic submucosal dissection: peroral traction-assisted endoscopic submucosal dissection
Gastrointest Endosc
(2009) - et al.
Endoscopic submucosal dissection of large colorectal tumors by using a novel spring-action S-O clip for traction (with video)
Gastrointest Endosc
(2009) - et al.
Prospective clinical trial of magnetic-anchor-guided endoscopic submucosal dissection for large early gastric cancer (with videos)
Gastrointest Endosc
(2009) - et al.
Magnamosis: magnetic compression anastomosis with comparison to suture and staple techniques
J Pediatr Surg
(2009) - et al.
Endoscopic mucosal resection for treatment of early gastric cancer
Gut
(2001) Endoscopic resection of early gastric cancer
Gastric Cancer
(2007)- et al.
Risk factors for complications of endoscopic submucosal dissection in gastric tumors: analysis of 478 lesions
J Gastroenterol
(2010) - et al.
Endoscopic submucosal dissection for colorectal neoplasia
Dig Endosc
(2010) - et al.
Efficacy of novel SB knife Jr examined in a multicenter study on colorectal endoscopic submucosal dissection
Dig Endosc
(2012)
A new technique for endoscopic submucosal dissection for early gastric cancer using an external grasping forceps
Endoscopy
Cited by (0)
DISCLOSURE: All authors disclosed no financial relationships relevant to this publication.