Before and After Study
Metabolic syndrome 2 years after laparoscopic gastric bypass

https://doi.org/10.1016/j.ijsu.2018.02.056Get rights and content
Under an Elsevier user license
open archive

Highlights

  • More than half of patients candidates to bariatric surgery present Metabolic Syndrome.

  • Bariatric surgery improves the metabolic syndrome and its components with results lasting after 2 years.

  • Other metabolic parameters important for cardiovascular risk during the 2 years are also positively affected.

  • There is a relationship between weight loss and metabolic syndrome improvement.

Abstract

Background

The latest diabetes consensus identified obesity as key component of the metabolic syndrome. The role of bariatric surgery over such syndrome has been less explored with a lack of long term studies, and especially among Mexicans.

Methods

Retrospective study including patients with metabolic syndrome submitted to laparoscopic gastric bypass at a single institution with complete data after 24 months. The objective was to analyze the improvement of the syndrome and each component. Demographic, anthropometric, biochemical and clinical parameters were analyzed at 12 and 24 months. Secondarily weight loss and other parameters were also analyzed. Finally, an analysis of syndrome improvement related to weight loss was performed.

Results

Sixty-three patients were included. The 2 most common components associated with obesity were reduced HDL and raised glucose or Type 2 diabetes. There was a significant improvement of metabolic syndrome and its components, as well as for the rest of the analyzed data, from the first check point and throughout follow-up. Prevalence of such syndrome was 6.3% at 12 and 24 months. Hypertension and raised glucose or Type 2 diabetes were the components with the greatest and fastest improvement; HDL levels and obesity were the least improved. There was a direct relationship between percentage of excess weight loss or percentage of excess BMI loss, and syndrome's improvement.

Conclusion

Patients with metabolic syndrome improved after gastric bypass, with results lasting after 2 years; other metabolic parameters important for cardiovascular risk were also positively affected. There was a relationship between the amount of weight loss and improvement of metabolic syndrome.

Keywords

Bariatric surgery
Metabolic syndrome
Hispanic
Latino
Mexican
Obesity
Type 2 diabetes mellitus
Hypertension
Laparoscopic gastric bypass

Abbreviations

AHA
American Heart Association
ATP
Adult Treatment Panel
IDF
International Diabetes Federation
MetS
Metabolic Syndrome
T2DM
Type 2 diabetes Mellitus
TG
triglycerides
HDL-C
HDL cholesterol
BP
Blood pressure
FPG
Fasting Plasma Glucose
BMI
Body mass index
% EWL
Percentage of excess weight loss
%EBMIL
Percentage of excess body mass index loss
LDL
Low density lipoprotein
HbA1c%
Glycated hemoglobin
SD
Standard deviation

Cited by (0)